Publications are listed by program and include publications published from July 2025 to June 2026.
Biochemistry and Molecular Biology
Adedola O. Adebamowo
Mentor: Nevil J. Singh, PhD
Boughter CT, Chatterjee B, Ohta Y, Gorga K, Blair C, Hill EM, Fasana Z, Adebamowo AO, Ammar F, Kosik I, Murugan V, Chen WH, Singh NJ, Meier-Schellersheim M. CountASAP: a lightweight, easy to use python package for processing ASAPseq data. BMC Bioinformatics. 2025 Nov 27;26(1):307. doi: 10.1186/s12859-025-06311-0. PMID: 41310452; PMCID: PMC12751127.
Issac Chaudry
Mentor: Jacques Ravel, PhD
France MT, Chaudry I, Rutt L, Quain M, Shirtliff B, McComb E, Maros A, Alizadeh M, Hussain FA, Elovitz MA, Relman DA, Rahman A, Brotman RM, Price JT, Kassaro MP, Holm JB, Ma B, Ravel J. VIRGO2: an enhanced gene catalog of the vaginal microbiome provides insights into its functional and ecology complexity. Nat Commun. 2025 Dec 6;17(1):449. doi: 10.1038/s41467-025-67136-2. PMID: 41353361.
France M, Chaudry I, Elsherbini J, Ravel J. kSanity: A k-mer based application for precision bacterial strain detection and quantification. bioRxiv [Preprint]. 2025 Sep 9:2025.09.04.674052. doi: 10.1101/2025.09.04.674052. PMID: 40964253; PMCID: PMC12439994.
Trebino MA, Kitts G, Haycocks JRJ, Wheat R, Chaudry I, Park JH, Erill I, Grainger DC, Yildiz FH. Parallel regulatory circuits orchestrate biofilm formation in response to c-di-GMP levels and growth phase. PLoS Genet. 2025 Sep 15;21(9):e1011870. doi: 10.1371/journal.pgen.1011870. PMID: 40953128; PMCID: PMC12456836.
Sudeep Khadka
Mentor: Jianfei Qi, PhD
Jeon HY, Khadka S, Pornour M, Ryu H, Chen H, Hussain A, Lam HM, Corey E, Oo HZ, Gleave M, Che X, Barbieri C, Qi J. BPTF regulates androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction. Nat Commun. 2025 Dec 11. doi: 10.1038/s41467-025-67329-9. Epub ahead of print. PMID: 41381516.
Joseph Kousouros
Mentor: Jonathan F. Fay, PhD
Fay JF, Kousouros J, Gao ZG, Pavan M, Oliva P, Pramanik A, Meyer C, Kurma SH, Xu W, Krumm B, Jacobson KA. UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor. Commun Biol. 2025 Nov 21;8(1):1816. doi: 10.1038/s42003-025-09174-6. PMID: 41272298; PMCID: PMC12738662.
Pramanik A, Wen Z, Pavan M, Kurma SH, Karcz T, Lewicki SA, Liu N, Demby T, Gavrilova O, Oliva P, Erlitz KS, Junker A, Jung YH, Chen Z, Salvemini D, Kousouros J, Gao ZG, Fay JF, Jacobson KA. P2Y14 Receptor Antagonists: Piperidine Bioisosteres and Mutagenesis-Supported Molecular Modeling. ACS Pharmacol Transl Sci. 2025 Aug 25;8(9):3126-3148. doi: 10.1021/acsptsci.5c00299. PMID: 40969903; PMCID: PMC12441858.
Yi Li
Mentor: Robert J. Bloch, PhD
Labuza A, Li Y, Rizzo MA, Bloch RJ. Small Ankyrin 1 Interacts with Phospholamban and Forms a Three-Way Complex with SERCA1. Biochemistry. 2025 Oct 7;64(19):4055-4066. doi: 10.1021/acs.biochem.5c00143. Epub 2025 Sep 25. PMID: 40998301.
Yaminisree Nagidi
Mentor: Min Yu, PhD
Oshima Y, Nagidi Y, Moorthy ME, Heier J, Matsubara JA, Hardin J, Flajnik M, Vogel BE. TEP-1, a glial thioester protein is required for cilia organization and intraflagellar transport in ensheathed sensory neurons. bioRxiv [Preprint]. 2025 Oct 24:2025.10.23.684198. doi: 10.1101/2025.10.23.684198. PMID: 41278702; PMCID: PMC12633222.
Ian P. O'Keefe
Mentor: Robert K. Ernst, PhD
O'Keefe IP, Putnam N, Ernst RK, Doub JB. A Pilot Study Using Microbial Glycolipid Signatures to Diagnose Nosocomial Ventriculitis. Rapid Commun Mass Spectrom. 2025 Dec 30;39(24):e10138. doi: 10.1002/rcm.10138. PMID: 40953911; PMCID: PMC12436068.
Jaishankar J, Yang H, O'Keefe IP, Tenaglia BM, Kinch LN, Ernst RK, Orth K. A critical role for Vibrio parahaemolyticus LPS to mediate evasion of host immune response during infection. Proc Natl Acad Sci U S A. 2025 Aug 19;122(33):e2426547122. doi: 10.1073/pnas.2426547122. Epub 2025 Aug 13. PMID: 40802686; PMCID: PMC12377781.
Mitasha Palha
Mentor: Joseph P. Kao, PhD
Kroenke CD, Canavesi I, Castro JN, Karpf JA, Khurana R, Holloway MM, Palha MS, Legenzov EA, Crilly NP, Epel B, Driesschaert B, Rawal VH, Kao JPY, Buehler PW, Roberts VHJ, Kotecha M. Trityl OXO71 Pharmacokinetics and Distribution in Rhesus Macaques. Magn Reson Med. 2025 Dec 15. doi: 10.1002/mrm.70214. Epub ahead of print. PMID: 41399038.
Karafin MS, Issaian AV, Bevers S, Reisz JA, Hay A, Keele GR, Dzieciatkowska M, Cendali FI, Haiman ZB, Key AM, Nemkov T, Stephenson D, Marsh E, Moore AL, Palha MS, Legenzov EA, Lamb DR, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Vallese F, Palsson BO, Spitalnik SL, Kao JPY, Roubinian NH, Janetzko J, Page GP, Eisenmesser EZ, Zimring JC, Buehler PW, D'Alessandro A. Genetic variation of human G6PD impacts Red Blood Cell transfusion efficacy. bioRxiv [Preprint]. 2025 Nov 22:2025.11.21.689741. doi: 10.1101/2025.11.21.689741. PMID: 41332617; PMCID: PMC12667890.
Epidemiology and Human Genetics
Ibrahim Ahmed El-Imam
Co-mentors: Surbhi Leekha, MBBS, MPH and Lyndsay M. O'Hara, PhD, MPH
GBD 2023 Lower Respiratory Infections and Antimicrobial Resistance Collaborators. Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023. Lancet Infect Dis. 2025 Dec 15:S1473-3099(25)00689-9. doi: 10.1016/S1473-3099(25)00689-9. Epub ahead of print. PMID: 41412141.
Ahmed El-Imam I, O'Hara LM, French I, Paskiewicz G, Robinson GL, Magder LS, Kristie Johnson J, Leekha S. Evaluation of hydrogen peroxide-based foam disinfection for reducing gram-negative bacterial contamination in hospital sinks. Infect Control Hosp Epidemiol. 2025 Nov 24:1-5. doi: 10.1017/ice.2025.10354. Epub ahead of print. PMID: 41277246.
Salma A. Bargal
Mentor: Amber L. Beitelshees, PharmD, MPH
El Rouby N, Aquilante CL, Bargal SA, Cavallari LH, Duarte JD, Gunderson K, Mazhindu T, Nagy M, Nie X, Nguyen DG, Patel JN, Skaar TC, Smith DM, Tuteja S, van Schaik RHN, Hicks JK; PGRN Implementation Working Group. Global Investigation of Clinical Implementation Strategies for DPYD Testing to Guide Fluoropyrimidine Therapy. Clin Transl Sci. 2026 Jan;19(1):e70466. doi: 10.1111/cts.70466. PMID: 41456101; PMCID: PMC12744196.
James Cottam
Mentor: Luana Colloca, MD, PhD, MS
Rodrigues B, Raghuraman N, Shafir R, Wang Y, Watson L, Cottam J, Nabi M, Akintola T, Colloca L. Placebo and nocebo effects. Pain. 2025 Nov 1;166(11S):S111-S115. doi: 10.1097/j.pain.0000000000003637. PMID: 41086341.
Mumtahana Nabi
Mentor: Luana Colloca, MD, PhD, MS
Rodrigues B, Raghuraman N, Shafir R, Wang Y, Watson L, Cottam J, Nabi M, Akintola T, Colloca L. Placebo and nocebo effects. Pain. 2025 Nov 1;166(11S):S111-S115. doi: 10.1097/j.pain.0000000000003637. PMID: 41086341.
Nginache Nampota
Mentor: Miriam K. Laufer, MD
Nyirenda OM, Moyo B, Divala T, Buchwald A, Nampota N, Mungwira R, Nyangulu W, Mkandawire F, Mwinjiwa E, Mallewa J, Laurens MB, Laufer MK, van Oosterhout JJ. Incident hypertension among adults on ART in Malawi: a nested cohort study. BMC Infect Dis. 2025 Dec 25. doi: 10.1186/s12879-025-12423-y. Epub ahead of print. PMID: 41449331.
Ebuka I. Onyenobi
Mentor: Sally N. Adebamowo, MBBS, MSc, ScD
Mitchell BD, Onyenobi E, Lewis JP, Gaynor B, Perry JA, Maloney K, O'Connell JR, Tiner J, Beitelshees AL, Van Hout CV, McArdle PF, Xu H, Puffenberger EG, Brigatti KW, Daue M, Whitlatch HB, Alkelai A, Schäffer AA, Overton J, Streeten EA, Pollin TI, Shuldiner AR. Exonic Variation and Its Clinical Impact in 7221 Old Order Amish. Am J Med Genet A. 2025 Dec;197(12):e64212. doi: 10.1002/ajmg.a.64212. Epub 2025 Aug 6. PMID: 40767373.
Onyenobi E, Oyibo K, Zhong M, Adebamowo SN. Evaluating the Impact of Family History and Polygenic Risk Scores on Cardiometabolic Disease Risk. Res Sq [Preprint]. 2025 Aug 1:rs.3.rs-7142452. doi: 10.21203/rs.3.rs-7142452/v1. PMID: 40766246; PMCID: PMC12324584.
Onyenobi E, Zhong M, Soremekun O, Kamiza A, Boua R, Chikowore T; ACCME Research Group; Fatumo S, Choudhury A, Hazelhurst S, Adebamowo C, Ramsay M, Tayo B, Albrecht JS, O'Connor TD, Zhang Y, Mitchell BD, Adebamowo SN. Correction to: Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations. Circ Genom Precis Med. 2025 Aug;18(4):e000099. doi: 10.1161/HCG.0000000000000099. Epub 2025 Jul 30. Erratum for: Circ Genom Precis Med. 2025 Jun;18(3):e005048. doi: 10.1161/CIRCGEN.124.005048. PMID: 40735786.
Knightess Oyibo
Mentor: Sally N. Adebamowo, MBBS, MSc, ScD
Onyenobi E, Oyibo K, Zhong M, Adebamowo SN. Evaluating the Impact of Family History and Polygenic Risk Scores on Cardiometabolic Disease Risk. Res Sq [Preprint]. 2025 Aug 1:rs.3.rs-7142452. doi: 10.21203/rs.3.rs-7142452/v1. PMID: 40766246; PMCID: PMC12324584.
Jessica Tiner
Mentor: Amber L. Beitelshees, PharmD, MPH
Mitchell BD, Onyenobi E, Lewis JP, Gaynor B, Perry JA, Maloney K, O'Connell JR, Tiner J, Beitelshees AL, Van Hout CV, McArdle PF, Xu H, Puffenberger EG, Brigatti KW, Daue M, Whitlatch HB, Alkelai A, Schäffer AA, Overton J, Streeten EA, Pollin TI, Shuldiner AR. Exonic Variation and Its Clinical Impact in 7221 Old Order Amish. Am J Med Genet A. 2025 Dec;197(12):e64212. doi: 10.1002/ajmg.a.64212. Epub 2025 Aug 6. PMID: 40767373.
Emma H. Rowley
Mentor: Shannon Takala Harrison, PhD
Guo B, Rowley E, O'Connor TD, Takala-Harrison S. Potential and pitfalls of using identity-by-descent for malaria genomic surveillance. Trends Parasitol. 2025 May;41(5):387-400. doi: 10.1016/j.pt.2025.03.012. Epub 2025 Apr 21. PMID: 40263027; PMCID: PMC12070291.
Zhenyao Ye
Mentor: Shuo Chen, PhD
Ma T, Ye Z, Feng L, Chen S. Lifestyle risk factors of white matter brain aging: evidence, potential mechanisms, and future direction. Neural Regen Res. 2026 Jan 2. doi: 10.4103/NRR.NRR-D-25-01039. Epub ahead of print. PMID: 41495609.
Chen C, Chen S, Ye Z, Shi X, Ma T, Shardell M. The Effect of Alcohol Intake on Brain White Matter Microstructural Integrity: A New Causal Inference Framework for Incomplete Phenomic Data. J Am Stat Assoc. 2025 Aug 5:10.1080/01621459.2025.2542553. doi: 10.1080/01621459.2025.2542553. Epub ahead of print. PMID: 41122496; PMCID: PMC12536561.
Salem D, Clark SM, Roche DJO, Singh NJ, Talor MV, Buchanan RW, Harrington V, Ye Z, Chen S, Kelly DL. T cells are associated with negative symptoms in persons with anti-gliadin antibody positive schizophrenia and related disorders. Schizophr Res. 2025 Oct;284:222-230. doi: 10.1016/j.schres.2025.08.008. Epub 2025 Aug 25. PMID: 40857980.
Gerontology
Alfred Boakye
Mentor: John G. Cagle, MSW, PhD
Park MK, Martin DJ, Boakye A, Mansour DZ, Bristow L. Navigating the storm: Insights for emergency planning for community-dwelling older adults-A report from focus groups with older adults and informal caregivers. J Emerg Manag. 2025 Sep-Oct;23(5):637-646. doi: 10.5055/jem.0927. PMID: 41171187.
Boakye A, Craft Morgan J, Kemp CL, Skipper AD. Understanding Trauma in the Context of Direct Care Work in Nursing Homes. J Appl Gerontol. 2025 Aug 11:7334648251364015. doi: 10.1177/07334648251364015. Epub ahead of print. PMID: 40790878.
Yoon Chung Kim
Mentor: Sarah Holmes, PhD, MSW
Holmes S, Rataj A, Wang J, Lepore M, Kusmaul N, Davie L, Kim YC, Murray B, Corazzini K. Collecting, Sharing, and Using Information for Person-Centered Dementia Care: Perspectives of Residents, Care Partners, and Staff in Low-Resource Long-Term Care Settings. J Appl Gerontol. 2025 Aug 17:7334648251369666. doi: 10.1177/07334648251369666. Epub ahead of print. PMID: 4082043
Molecular Medicine
Dipanwita Dutta Chowdhury
Mentor: Phuoc T. Tran, MD, PhD
Lafargue A, Wang H, Chettiar ST, Gajula RP, Shetty AC, Song Y, Simons BW, Khan MA, Nguyen T, Tseng HW, Chang J, Waters DN, Chan A, Lam C, Carrieri FA, Smack C, Connis N, Chowdhury DD, Nugent K, Siddiqui I, Taparra K, Rezaee M, Zachara N, Morris ZS, McFarland C, Abdulkadir SA, Hann CL, Tran PT. Twist1-induced suppression of oncogene-induced senescence in non-small cell lung cancer requires the transactivation domain of Twist1. Neoplasia. 2025 Aug;66:101179. doi: 10.1016/j.neo.2025.101179. Epub 2025 May 22. PMID: 40409044; PMCID: PMC12148720.
Zachary Fasana
Mentor: Nevil Singh, PhD
Boughter CT, Chatterjee B, Ohta Y, Gorga K, Blair C, Hill EM, Fasana Z, Adebamowo AO, Ammar F, Kosik I, Murugan V, Chen WH, Singh NJ, Meier-Schellersheim M. CountASAP: a lightweight, easy to use python package for processing ASAPseq data. BMC Bioinformatics. 2025 Nov 27;26(1):307. doi: 10.1186/s12859-025-06311-0. PMID: 41310452; PMCID: PMC12751127.
Katie Ko
Mentor: David Serre, Dr. rer. nat.
Ko K, Tebben K, Andrianinarivomanana T, Orban A, Grünebast J, Eng V, Eam R, Khim N, Feufack-Donfack L, Salvador J, Sá J, Wellems T, Lek D, Popovici J, Serre D. A common DNA deletion altering the 3'UTR of mdr1 is associated with reduced mefloquine susceptibility in P. vivax parasites from Cambodian patients. Res Sq [Preprint]. 2025 Sep 1:rs.3.rs-6889263. doi: 10.21203/rs.3.rs-6889263/v1. PMID: 40951274; PMCID: PMC12425083.
Amir Mehrabani Tabari
Mentor: Marta M. Lipinski, PhD
Mehrabani-Tabari AA, Hegdekar N, Herb BR, Kachi SA, Sarkar C, Thapa S, Nguyen DP, Morel Y, Weldemariam MM, Muller L, Temple Andrews W, Cortes-Gutierrez M, Fan X, Ayithan N, Pettyjohn-Robin O, Bustos S, Greer LK, Gore JT, Kane MA, Ament SA, Jones JW, Lipinski MM. Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury. Res Sq [Preprint]. 2025 Oct 21:rs.3.rs-7682363. doi: 10.21203/rs.3.rs-7682363/v1. PMID: 41282218; PMCID: PMC12633487.
Ian Mills
Mentor: Daria A. Gaykalova, PhD
Choudhury SR, Gupta I, Mills I, Mukhina V, Loginov A, Allor E, Anderson A, Cellini A, Robles C, Dyalram D, Lubek J, Wolf J, Taylor R, Hatten K, Vorobyeva N, Gaykalova DA. HOXC6 overexpression stimulates cell migration and correlates with poor prognosis in head and neck squamous cell carcinoma. Cell Mol Life Sci. 2026 Jan 11. doi: 10.1007/s00018-025-06039-3. Epub ahead of print. PMID: 41521225.
Rendina BP, Ahmad F, Akerman L, Mills I, Lee NC, Chen C, Ren H, Fan X, Winkles JA, Woodworth GF, Wilson GM, Bar EE. Post-transcriptional control of HIF-1α by MBNL1 restrains hypoxia-driven stemness in GBM. Neoplasia. 2025 Dec 8;72:101262. doi: 10.1016/j.neo.2025.101262. Epub ahead of print. PMID: 41365085; PMCID: PMC12743534.
Riccardo Serra
Mentor: Graeme F. Woodworth, MD, BS
Zhao T, Serra R, Guo M, Premananthan S, Connis N, Ji C, Rincon-Torroella J, Williamson T, Tyler B, Burger P, Rooper LM, Eberhart C, Hann CL, Gallia GL. Inhibition of CDKs Enhances Efficacy of Anti-EGFR Therapy in Chordoma. Mol Cancer Ther. 2025 Dec 4. doi: 10.1158/1535-7163.MCT-24-0962. Epub ahead of print. PMID: 41340469.
Stokum JA, Wilhelmy B, Bragança C, Tosun C, Serra R, Tsymbalyuk O, Keledjian K, Gerzanich V, Simard JM. Amiodarone Improves Locomotor Function in Experimental Spinal Cord Injury by Reducing Secondary Axonal Degeneration and White Matter Atrophy. J Neurotrauma. 2025 Nov 25. doi: 10.1177/08977151251400735. Epub ahead of print. PMID: 41314966.
Serra R, Mahapatra S, Huq S, Meggyesy M, Gorelick NL, Manthripragada L, Moghekar A, Luciano MG. A retrospective longitudinal analysis of risk factors, treatment outcomes and imaging parameters of ventricular collapse in idiopathic intracranial hypertension. Fluids Barriers CNS. 2025 Nov 5;22(1):112. doi: 10.1186/s12987-025-00717-x. PMID: 41194161; PMCID: PMC12587583.
Jhajharia A, Moyer M, Olu-Owotade J, McAfee D, Eldirdiri A, Rogers J, Zhu M, Boddeti U, Serra R, Simard JM, Gerzanich V, Bachani M, Mayer D, Ksendzovsky A. Hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging identifies elevated lactate in epileptic tissue. Brain Commun. 2025 Sep 13;7(5):fcaf357. doi: 10.1093/braincomms/fcaf357. PMID: 41020176; PMCID: PMC12464677.
Sagarina Thapa
Mentor: Xuefang Cao, PhD
Mehrabani-Tabari AA, Hegdekar N, Herb BR, Kachi SA, Sarkar C, Thapa S, Nguyen DP, Morel Y, Weldemariam MM, Muller L, Temple Andrews W, Cortes-Gutierrez M, Fan X, Ayithan N, Pettyjohn-Robin O, Bustos S, Greer LK, Gore JT, Kane MA, Ament SA, Jones JW, Lipinski MM. Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury. Res Sq [Preprint]. 2025 Oct 21:rs.3.rs-7682363. doi: 10.21203/rs.3.rs-7682363/v1. PMID: 41282218; PMCID: PMC12633487.
Kaylee Watson
Mentor: Julie C. Dunning-Hotopp, PhD
Grünebast J, Singhal R, Bromley R, Kanatani S, Watson K, Olson S, Dumetz F, Pascini TV, Tripathi A, Dunning Hotopp JC, Sinnis P, Llinás M, Serre D. Degradation of ribosomal RNA during Plasmodium falciparum gametocytogenesis. mBio. 2025 Nov 12;16(11):e0256525. doi: 10.1128/mbio.02565-25. Epub 2025 Sep 22. PMID: 40980880; PMCID: PMC12607831.
Molecular Microbiology and Immunology
Yonit A. Addissie
Co-mentors: Nevil J. Singh, PhD, and Stanley Lipkowitz, MD, PhD
Wisniewski DJ, Voeller D, Addissie YA, Deshmukh SK, Wu S, Lustberg MB, Wangsa D, Wangsa D, Heselmeyer-Haddad K, Greer YE, Sledge GW, Lipkowitz S. EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition. Oncogene. 2026 Jan;45(1):15-25. doi: 10.1038/s41388-025-03634-3. Epub 2025 Nov 25. PMID: 41291067; PMCID: PMC12714574.
Jillian M. Baker
Mentor: Tim C. Luetkens, MD
Hardy NM, Yared JA, Luetkens T, Ahmad H, Mulatu R, Yamoah D, Fan X, Weeks S, Bredar SA, Gelin A, Baker JM, Dietze KA, Matsangos A, Fromowitz A, Theruvath J, Wirthlin L, Kaleta R, Wijatyk A, Koka R, Kallen ME, Hankey KG, Rapoport AP, Atanackovic D. CNS infiltration by zamtocabtagene autoleucel tandem CD20/CD19 CAR T cells leading to complete remission in a patient with primary CNS lymphoma. Haematologica. 2025 Oct 16. doi: 10.3324/haematol.2025.288856. Epub ahead of print. PMID: 41098100.
Baker JM, Wang A, Dietze KA, Atanackovic D, Luetkens T. A novel sweeping antibody exhibits efficient clearance of the cancer- and autoimmunity-associated cytokine interleukin 16. bioRxiv [Preprint]. 2025 Aug 1:2025.07.29.666814. doi: 10.1101/2025.07.29.666814. PMID: 40766633; PMCID: PMC12324265.
Ella Brunsting
Mentor: Darren J. Perkins, PhD
Brunsting EL, Perkins DJ. Working in negative space: Type I interferon mediated immuno-modulation through transcriptional suppression in disease and homeostasis. Innate Immun. 2025 Jan-Dec;31:17534259251367263. doi: 10.1177/17534259251367263. Epub 2025 Aug 18. PMID: 40827030; PMCID: PMC12365442.
Kenneth A. Dietze
Mentor: Tim C. Luetkens, MD
Hardy NM, Yared JA, Luetkens T, Ahmad H, Mulatu R, Yamoah D, Fan X, Weeks S, Bredar SA, Gelin A, Baker JM, Dietze KA, Matsangos A, Fromowitz A, Theruvath J, Wirthlin L, Kaleta R, Wijatyk A, Koka R, Kallen ME, Hankey KG, Rapoport AP, Atanackovic D. CNS infiltration by zamtocabtagene autoleucel tandem CD20/CD19 CAR T cells leading to complete remission in a patient with primary CNS lymphoma. Haematologica. 2025 Oct 16. doi: 10.3324/haematol.2025.288856. Epub ahead of print. PMID: 41098100.
Baker JM, Wang A, Dietze KA, Atanackovic D, Luetkens T. A novel sweeping antibody exhibits efficient clearance of the cancer- and autoimmunity-associated cytokine interleukin 16. bioRxiv [Preprint]. 2025 Aug 1:2025.07.29.666814. doi: 10.1101/2025.07.29.666814. PMID: 40766633; PMCID: PMC12324265.
Atanackovic D, Luetkens T, Schneider D, Hu P, Wang X, Shetty AC, Tallon L, Patel I, Singh R, Gebru E, Mulatu R, Omili D, Yamoah D, Fan X, Matsangos A, Lesho P, Dietze KA, Fromowitz AA, Hankey KG, Dahiya S, Yared JA, Hardy NM, Koka R, Kallen ME, Badros A, Rapoport AP, Kocoglu MH. Immune correlates of anti-BCMA CAR-T products idecabtagene vicleucel and ciltacabtagene autoleucel in a real-world cohort of patients with multiple myeloma. Nat Commun. 2025 Jul 4;16(1):6154. doi: 10.1038/s41467-025-60980-2. PMID: 40610432; PMCID: PMC12229333.
Valerie Harrington
Mentor: David A. Rasko, PhD
Murray SL, Vyas G, Eberhardt E, Roche DJO, Adams HA, Harrington V, Kearns A, Glassman M, Yuen A, Chiappelli J, Pugh S, Barron B, Sandow K, Palmer CM, Kelly DL. Case Report: Metabolic, inflammatory, and neurological improvements after a ketogenic diet in a woman with treatment-resistant schizophrenia and metabolic syndrome. Front Psychiatry. 2025 Nov 20;16:1710785. doi: 10.3389/fpsyt.2025.1710785. PMID: 41356674; PMCID: PMC12677013.
Elizabeth M. Hill
Mentor: Nevil J. Singh, PhD
Ay B, Cyr SM, Iwasaki Y, Hill E, Rhee EP, Singh NJ, Simic P, Bastepe M. Lysophosphatidic Acid Synergizes With 1,25-Dihydroxyvitamin D to Promote Fibroblast Growth Factor-23 Synthesis via MAPK Signaling and Induction of the IL12A Gene. FASEB J. 2026 Jan 15;40(1):e71435. doi: 10.1096/fj.202502235R. PMID: 41511413; PMCID: PMC12786602.
Boughter CT, Chatterjee B, Ohta Y, Gorga K, Blair C, Hill EM, Fasana Z, Adebamowo AO, Ammar F, Kosik I, Murugan V, Chen WH, Singh NJ, Meier-Schellersheim M. CountASAP: a lightweight, easy to use python package for processing ASAPseq data. BMC Bioinformatics. 2025 Nov 27;26(1):307. doi: 10.1186/s12859-025-06311-0. PMID: 41310452; PMCID: PMC12751127.
Chatterjee B, Gorga K, Blair C, Ohta Y, Hill EM, Boughter CT, Meier-Schellersheim M, Singh NJ. Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments. bioRxiv [Preprint]. 2025 Oct 17:2025.10.16.682943. doi: 10.1101/2025.10.16.682943. PMID: 41278914; PMCID: PMC12632948.
Bernadette Hritzo
Mentor: David A. Rasko, PhD
Hritzo BA, Michalski JM, Rasko DA. Characterization of the role of putative Aeromonas caviae-specific virulence factor, flgB, in virulence and host-pathogen interactions. J Bacteriol. 2025 Dec 29:e0033925. doi: 10.1128/jb.00339-25. Epub ahead of print. PMID: 41459941.
Hritzo BA, Michalski Wilhelm JM, Rasko DA. Genomes of enteric pathogen isolates from polymicrobial infections in cases of pediatric diarrhea. Microbiol Resour Announc. 2026 Jan 13;15(1):e0101525. doi: 10.1128/mra.01015-25. Epub 2025 Dec 5. PMID: 41347464; PMCID: PMC12797964.
Hritzo BA, Michalski JM, Sikorski MJ, Rasko DA. Complete genomes of hybrid Escherichia coli isolates containing virulence factors from enterotoxigenic and enteropathogenic pathovars. Microbiol Resour Announc. 2025 Dec 11;14(12):e0095925. doi: 10.1128/mra.00959-25. Epub 2025 Nov 10. PMID: 41211973; PMCID: PMC12697144.
Michalski JM, Hritzo BA, Jones JA, Permala-Booth J, Tennant SM, Rasko DA. Draft genomes of Aeromonas species isolated from humans. Microbiol Resour Announc. 2025 Nov 13;14(11):e0075725. doi: 10.1128/mra.00757-25. Epub 2025 Oct 21. PMID: 41117557; PMCID: PMC12613984.
Rach D, Hsu HT, Nampota-Nkomba N, Mvula G, Mkandawire FA, Nyirenda OM, Hritzo B, Boldrin F, Degiacomi G, Mazzabò LC, Manganelli R, Buchwald AG, Toapanta FR, Sztein MB, Laufer MK, Lyke KE, Cairo C. Cord blood innate-like T cell responses in neonates born to healthy women and women living with HIV. Front Immunol. 2025 Aug 22;16:1628145. doi: 10.3389/fimmu.2025.1628145. PMID: 40918102; PMCID: PMC12412222.
Alexander Laurenson
Mentor: Matthew B. Laurens, MD, MPH
Laurenson AJ, Pierce BG, Takala-Harrison S, Laurens MB. Computational Prioritization of T Cell Epitopes to Overcome HLA Restriction and Antigenic Diversity in Plasmodium falciparum. bioRxiv [Preprint]. 2025 Jul 18:2025.07.14.664425. doi: 10.1101/2025.07.14.664425. PMID: 40791414; PMCID: PMC12338633.
Nina C. Lee
Mentor: Gerald M. Wilson, PhD
Rendina BP, Ahmad F, Akerman L, Mills I, Lee NC, Chen C, Ren H, Fan X, Winkles JA, Woodworth GF, Wilson GM, Bar EE. Post-transcriptional control of HIF-1α by MBNL1 restrains hypoxia-driven stemness in GBM. Neoplasia. 2025 Dec 8;72:101262. doi: 10.1016/j.neo.2025.101262. Epub ahead of print. PMID: 41365085; PMCID: PMC12743534.
Erica Leyder
Mentor: Alexander S. Krupnick, MD
Leyder E, Taheri M, Neschis M, Banerjee A, Jacobsen EA, Gelman A, Kreisel D, Krupnick AS, Mei Z. Unique Immune Polarization of the Lung Allograft: Implications for Organ-specific Immunoregulation and Tolerance Induction. Transplantation. 2025 Sep 17:10.1097/TP.0000000000005521. doi: 10.1097/TP.0000000000005521. Epub ahead of print. PMID: 40958148; PMCID: PMC12503030.
Yaoxian Lou
Mentor: Lishan Su, PhD
Li G, Lou Y, Ma J, Cheng L, Yu H, Tsahouridis O, He X, Funaki M, Ahodantin J, Bi W, Chen J, Fan X, Sharaf S, Goonetilleke N, Jones RB, Kottilil S, Mathur P, Su L. Depletion of plasmacytoid dendritic cells rescues HIV-reactive stem-like CD8+ T cells during chronic HIV-1 infection. Sci Transl Med. 2025 Nov 5;17(823):eadr3930. doi: 10.1126/scitranslmed.adr3930. Epub 2025 Nov 5. PMID: 41191775.
Li G, Ma J, Yu H, Tsahouridis O, Lou Y, He X, Funaki M, Zheng P, Liu Y, Su L. CD24-Fc resolves inflammation and enhances anti-HIV CD8 T cells with polyfunctionality during HIV-1 infection under cART. PLoS Pathog. 2025 Aug 8;21(8):e1012826. doi: 10.1371/journal.ppat.1012826. PMID: 40779581; PMCID: PMC12349878.
Jernelle C. Miller
Mentor: Sharon M. Tennant, PhD
Miller JC, Choi M, Zhao Z, Mushrush EM, Legesse TB, Cross AS, Baliban SM, Tennant SM. Development of a mouse model for Klebsiella pneumoniae-associated neonatal sepsis. Microbiol Spectr. 2025 Sep 2;13(9):e0069725. doi: 10.1128/spectrum.00697-25. Epub 2025 Aug 1. PMID: 40748073; PMCID: PMC12403570..
Destiny Omili
Mentor: Stuart S. Martin, PhD
Atanackovic D, Luetkens T, Schneider D, Hu P, Wang X, Shetty AC, Tallon L, Patel I, Singh R, Gebru E, Mulatu R, Omili D, Yamoah D, Fan X, Matsangos A, Lesho P, Dietze KA, Fromowitz AA, Hankey KG, Dahiya S, Yared JA, Hardy NM, Koka R, Kallen ME, Badros A, Rapoport AP, Kocoglu MH. Immune correlates of anti-BCMA CAR-T products idecabtagene vicleucel and ciltacabtagene autoleucel in a real-world cohort of patients with multiple myeloma. Nat Commun. 2025 Jul 4;16(1):6154. doi: 10.1038/s41467-025-60980-2. PMID: 40610432; PMCID: PMC12229333.
David Rach
Mentors: Cristiana Cairo, PhD and Kirsten E. Lyke, MD
Rach D, Hsu HT, Nampota-Nkomba N, Mvula G, Mkandawire FA, Nyirenda OM, Hritzo B, Boldrin F, Degiacomi G, Mazzabò LC, Manganelli R, Buchwald AG, Toapanta FR, Sztein MB, Laufer MK, Lyke KE, Cairo C. Cord blood innate-like T cell responses in neonates born to healthy women and women living with HIV. Front Immunol. 2025 Aug 22;16:1628145. doi: 10.3389/fimmu.2025.1628145. PMID: 40918102; PMCID: PMC12412222.
David M. Rickert
Mentor: Nicholas H. Carbonetti, PhD
Rickert DM, Cardozo S, Carbonetti NH, Goldman WE, Scanlon KM, Skerry C. A dual role for PGLYRP1 in host defense and immune regulation during B. pertussis infection. bioRxiv [Preprint]. 2025 Sep 27:2025.09.26.678899. doi: 10.1101/2025.09.26.678899. PMID: 41040336; PMCID: PMC12485853.
Marnin L, Valencia LM, Bogale HN, Laukaitis-Yousey HJ, Rolandelli A, Ferraz CR, O'Neal AJ, Schmitter-Sánchez AD, Cuevas EB, Nguyen TT, Leal-Galvan B, Rickert DM, Mendes MT, Samaddar S, Butler LR, Singh N, Cabrera Paz FE, Wu-Chuang A, Oliver JD, Jameson JM, Munderloh UG, Oliva Chávez AS, Mulenga A, Park S, Serre D, Pedra JHF. Tick Extracellular Vesicles Alter Epidermal Keratinocyte Function. J Invest Dermatol. 2025 Sep 5:S0022-202X(25)02414-5. doi: 10.1016/j.jid.2025.08.037. Epub ahead of print. PMID: 40915408; PMCID: PMC12603915.
Cosette Schneider
Mentor: Lynda Coughlan, PhD
Deming ME, Toapanta FR, Pasetti M, Golding H, Khurana S, Hamouda T, Fattom A, Liang Y, Tennant SM, McGilvray MF, Bernal PJ, Oshinsky JJ, Datta S, Booth JP, Coughlan L, Neuzil KM, Costley CD, Kotloff KL, Sztein MB, Ortiz JR; rH5 Writing Group. An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial. Nat Commun. 2025 Nov 6;16(1):9321. doi: 10.1038/s41467-025-64686-3. PMID: 41198655; PMCID: PMC12592354.
Werner AP, Schneider CG, Akin EH, Hayes J, Fenstermacher KZJ, Rothman RE, Coughlan L, Pekosz A. Low levels of influenza H5N1 HA and NA antibodies in the human population are boosted by seasonal H1N1 infection but not by H3N2 infection or influenza vaccination. mBio. 2025 Dec 10;16(12):e0214525. doi: 10.1128/mbio.02145-25. Epub 2025 Oct 31. PMID: 41170854; PMCID: PMC12691596.
Seibert BA, Parish MA, Talukdar SN, Zhang T, Chaulagain S, Liu JA, Sachithanandham J, Schneider C, Coughlan L, Bowman A, Webby RJ, Harkema JR, Pekosz A, Klein SL. Vertical Transmission of Bovine H5N1 during Pregnancy and Lactation in Mice. bioRxiv [Preprint]. 2025 Jul 27:2025.07.07.663583. doi: 10.1101/2025.07.07.663583. PMID: 40672328; PMCID: PMC12265628.
Luisa M. Valencia
Mentor: Joao H.F. Pedra, PhD
Marnin L, Valencia LM, Bogale HN, Laukaitis-Yousey HJ, Rolandelli A, Ferraz CR, O'Neal AJ, Schmitter-Sánchez AD, Cuevas EB, Nguyen TT, Leal-Galvan B, Rickert DM, Mendes MT, Samaddar S, Butler LR, Singh N, Cabrera Paz FE, Wu-Chuang A, Oliver JD, Jameson JM, Munderloh UG, Oliva Chávez AS, Mulenga A, Park S, Serre D, Pedra JHF. Tick Extracellular Vesicles Alter Epidermal Keratinocyte Function. J Invest Dermatol. 2025 Sep 5:S0022-202X(25)02414-5. doi: 10.1016/j.jid.2025.08.037. Epub ahead of print. PMID: 40915408; PMCID: PMC12603915.
Neuroscience
Daniela Franco
Mentor: Mary Kay Lobo, PhD
Campbell RR, Green M, Choi EY, Wulff AB, Siclair AN, Khatri S, Virata G, Barrett C, Key S, Patel S, Rowell MB, Franco D, Ganapathy-Kanniappan S, Mathur BN, Lobo MK. Dopamine Receptor 1 Specific CRISPRa Mice Exhibit Disrupted Behaviors and Striatal Baseline Cellular Activity. eNeuro. 2025 Aug 18;12(8):ENEURO.0157-25.2025. doi: 10.1523/ENEURO.0157-25.2025. PMID: 40707359; PMCID: PMC12360625.
Mikah S. Green
Mentor: Mary Kay Lobo, PhD
Campbell RR, Green M, Choi EY, Wulff AB, Siclair AN, Khatri S, Virata G, Barrett C, Key S, Patel S, Rowell MB, Franco D, Ganapathy-Kanniappan S, Mathur BN, Lobo MK. Dopamine Receptor 1 Specific CRISPRa Mice Exhibit Disrupted Behaviors and Striatal Baseline Cellular Activity. eNeuro. 2025 Aug 18;12(8):ENEURO.0157-25.2025. doi: 10.1523/ENEURO.0157-25.2025. PMID: 40707359; PMCID: PMC12360625.
Lacey Kennedy Greer
Mentors: Thomas A. Blanpied, PhD and Brandon Harvey, PhD
Mehrabani-Tabari AA, Hegdekar N, Herb BR, Kachi SA, Sarkar C, Thapa S, Nguyen DP, Morel Y, Weldemariam MM, Muller L, Temple Andrews W, Cortes-Gutierrez M, Fan X, Ayithan N, Pettyjohn-Robin O, Bustos S, Greer LK, Gore JT, Kane MA, Ament SA, Jones JW, Lipinski MM. Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury. Res Sq [Preprint]. 2025 Oct 21:rs.3.rs-7682363. doi: 10.21203/rs.3.rs-7682363/v1. PMID: 41282218; PMCID: PMC12633487.
Maxwell Madden
Mentor: Brian N. Mathur, PhD
Madden MB, Schaefgen C, Vedak B, Kwon J, Pedra KSD, Sheats SH, Puche AC, Wolff SBE, Mathur BN. Serotonin and psilocybin activate 5-HT1B receptors to suppress cortical signaling through the claustrum. Nat Commun. 2025 Aug 19;16(1):7733. doi: 10.1038/s41467-025-62980-8. PMID: 40830107; PMCID: PMC12365098.
Phuoc (Dexter) Nguyen
Mentor: Marta M. Lipinski, PhD
Mehrabani-Tabari AA, Hegdekar N, Herb BR, Kachi SA, Sarkar C, Thapa S, Nguyen DP, Morel Y, Weldemariam MM, Muller L, Temple Andrews W, Cortes-Gutierrez M, Fan X, Ayithan N, Pettyjohn-Robin O, Bustos S, Greer LK, Gore JT, Kane MA, Ament SA, Jones JW, Lipinski MM. Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury. Res Sq [Preprint]. 2025 Oct 21:rs.3.rs-7682363. doi: 10.21203/rs.3.rs-7682363/v1. PMID: 41282218; PMCID: PMC12633487.
Aiden L. Pham
Mentor: Margaret M. McCarthy, PhD
Pham AL, Marquardt AE, Montgomery KR, Sobota KN, McCarthy MM, VanRyzin JW. Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala. Neuropsychopharmacology. 2025 Oct;50(11):1655-1664. doi: 10.1038/s41386-025-02173-5. Epub 2025 Jul 23. PMID: 40702164; PMCID: PMC12436615.
Meghann C. Ryan
Mentor: Linda Chang, MD, MS
Ryan M, Thomas J, Wang J, Liang H, Cunningham E, Ernst T, Chang L. Structural Brain Abnormalities and Neuropsychiatric Symptoms in Post-COVID Condition. NeuroImmune Pharm Ther. 2025 Nov 17:10.1515/nipt-2025-0012. doi: 10.1515/nipt-2025-0012. Epub ahead of print. PMID: 41346653; PMCID: PMC12674627.
Hassan Saadi
Mentor: Graeme F. Woodworth, MD, B.S.
Odell J, Tang Y, Ambekar YS, Kidiyoor GR, Saadi H, Woodworth GF, Holt LJ, Scarcelli G, Yu H, Lammerding J. The Deformability of the Mammalian Cell Nucleus is Determined by the Identity of the Lamin Rod Domain. bioRxiv [Preprint]. 2025 Jul 22:2025.07.22.666133. doi: 10.1101/2025.07.22.666133. PMID: 40777269; PMCID: PMC12330664.
Chloe Schaefgen
Mentor: Brian N. Mathur, PhD
Madden MB, Schaefgen C, Vedak B, Kwon J, Pedra KSD, Sheats SH, Puche AC, Wolff SBE, Mathur BN. Serotonin and psilocybin activate 5-HT1B receptors to suppress cortical signaling through the claustrum. Nat Commun. 2025 Aug 19;16(1):7733. doi: 10.1038/s41467-025-62980-8. PMID: 40830107; PMCID: PMC12365098.
Allison Siclair
Mentor: Brian N. Mathur
Campbell RR, Green M, Choi EY, Wulff AB, Siclair AN, Khatri S, Virata G, Barrett C, Key S, Patel S, Rowell MB, Franco D, Ganapathy-Kanniappan S, Mathur BN, Lobo MK. Dopamine receptor 1 specific CRISPRa mice exhibit disrupted behaviors and striatal baseline cellular activity. eNeuro. 2025 Jul 24:ENEURO.0157-25.2025. doi: 10.1523/ENEURO.0157-25.2025. Epub ahead of print. PMID: 40707359.
Patton MS, Sheats SH, Wulff AB, McKeon PN, VanRyzin JW, Patton MH, Heckman M, Siclair AN, Iffland PH, Mathur BN. Perineuronal Net and Inhibitory Synapse Remodeling on Striatal Fast-spiking Interneurons by Chronic Alcohol Exposure. bioRxiv [Preprint]. 2025 Jul 12:2025.07.08.663744. doi: 10.1101/2025.07.08.663744. PMID: 40672273; PMCID: PMC12265726.
Binita Vedak
Mentor: Maged M. Harraz, MB,BCh, MS, PhD
Madden MB, Schaefgen C, Vedak B, Kwon J, Pedra KSD, Sheats SH, Puche AC, Wolff SBE, Mathur BN. Serotonin and psilocybin activate 5-HT1B receptors to suppress cortical signaling through the claustrum. Nat Commun. 2025 Aug 19;16(1):7733. doi: 10.1038/s41467-025-62980-8. PMID: 40830107; PMCID: PMC12365098.
Lakota Watson
Mentor: Luana Colloca, MD, PhD
Watson L, Wang Y, White JN, Shafir R, Colloca G, Heagerty JM, Li S, Brawn B, Varshney A, Chen S, Colloca L. Effects of childhood adversity on socially learned placebo analgesia in virtual reality: A cross-sectional study. medRxiv [Preprint]. 2025 Dec 9:2025.12.04.25341572. doi: 10.64898/2025.12.04.25341572. PMID: 41404275; PMCID: PMC12704645.
Rodrigues B, Raghuraman N, Shafir R, Wang Y, Watson L, Cottam J, Nabi M, Akintola T, Colloca L. Placebo and nocebo effects. Pain. 2025 Nov 1;166(11S):S111-S115. doi: 10.1097/j.pain.0000000000003637. PMID: 41086341.
Naibo Zhang
Mentor: Brian M. Polster, PhD
Zhang N, Roelofs BA, Bordt EA, Piskoun B, Robertson CL, Polster BM. CRABS-ROC, A respirometry protocol for overcoming substrate limitations, reveals excess brain mitochondrial Complex I capacity. Free Radic Biol Med. 2025 Dec 16;241:24-31. doi: 10.1016/j.freeradbiomed.2025.09.011. Epub 2025 Sep 9. PMID: 40935348; PMCID: PMC12776583.